Reggio di Calabria, commonly known as Reggio Calabria or simply Reggio in Southern Italy, is the biggest city and the most populated comune of Calabria, Southern Italy. It is the capital of the Metropolitan City of Reggio Calabria and the seat of the Regional Council of Calabria.

Reggio is located on the "toe" of the Italian Peninsula and is separated from the island of Sicily by the Strait of Messina. It is situated on the slopes of the Aspromonte, a long, craggy mountain range that runs up through the center of the region. The third economic center of mainland Southern Italy, is the oldest city in the region.

As a major functional pole in the region, it has strong historical, cultural and economic ties with the city of Messina, which lies across the strait in Sicily, forming a metro city of less than 1 million people.